Downtown Orlando is the historic core and central business district of Orlando, Florida, United States. It is bordered by Marks Street in the north, Mills Avenue in the east, Orange Blossom Trail in the west, and Kaley Avenue in the south. There are several distinct neighborhoods in downtown; "North Quarter" to the north, "Lake Eola Heights Historic …Downtown Orlando is the historic core and central business district of Orlando, Florida, United States. It is bordered by Marks Street in the north, Mills Avenue in the east, Orange Blossom Trail in the west, and Kaley Avenue in the south. There are several distinct neighborhoods in downtown; "North Quarter" to the north, "Lake Eola Heights Historic District" just north of Lake Eola, "South Eola" contains Lake Eola Park and continues to the east and south of Lake Eola, "Thornton Park" in the east, "Parramore" in the west, "Lake Cherokee Historic District" to the south, and the "Central Business District" between Colonial Drive and Lake Lucerne in the center. In 2010, the estimated population of downtown was 18,731. The daytime population was estimated to be 65,000. The 5-mile radius population of downtown is 273,335.