Fibrosis and accumulation of senescent cells are common tissue changes associated with aging. Here, we show that the CDK ...

In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...

The intracellular bacterial pathogen Coxiella burnetii secretes an effector protein, CbEPF1, which manipulates LD metabolism ...

The systemic regulation of metabolic dysfunction-associated liver disease remains poorly understood. In this issue, Hsiao et ...

The time bomb of misinformation and disinformation will have exploded, taking with it our ability to think for ourselves.

The liver function in post-cardiac arrest brain injury is not known and was investigated in a pig model of global cerebral ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

Astrocytes in the brain exhibit significant regional diversity, but the mechanisms controlling their heterogeneity remain ...

MDA5 is a critical cytoplasmic RNA sensor capable of triggering type I interferon pathways. This study shows that the E3 ...

K Heran Darwin is at New York University Grossman School of Medicine and a regular columnist for EMBO reports.

A machine-learning method predicts whether a genetic variant is pathogenic and affects certain human tissues. The ...

It is boomtime for metabolism and metabolomics research. One hundred years after Otto Warburg put metabolism at the core of ...