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The EMBO Journal
13m
p21 regulates expression of ECM components and promotes pulmonary fibrosis via CDK4 and Rb
Fibrosis and accumulation of senescent cells are common tissue changes associated with aging. Here, we show that the CDK ...
The EMBO Journal
13m
Cellular senescence, p21, and the path to fibrosis
In this issue, Papismadov et al (2024) report that p21 (CDKN1A), known to activate the senescence growth arrest, also ...
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